Cerenion C-Trend® was used in a scientific article entitled “Monitoring of night time EEG slow‐wave activity during dexmedetomidine infusion in patients with hyperactive ICU delirium: An observational pilot study” recently published in Acta Anaesthesiologica Scandinavica.
The disturbance of especially deep stages of sleep has been associated with intensive care unit (ICU) delirium, which is a severe condition of brain dysfunction associated with e.g. prolonged hospitalization, higher mortality, and long-term cognitive impairment. Monitoring and improving the sleep quality in the ICU potentially reduces the risk of delirium. In the published pilot study, C-Trend® was used for objective evaluation of slow-wave activity, an EEG feature occurring during deep sleep, in ICU patients diagnosed with hyperactive delirium. The study confirmed previous findings of poor sleep quality in these patients and emphasized the necessity of objective sleep evaluation during intensive care.
The study was carried out in collaboration with Oulu University Hospital and the University of Oulu. It is available as open access at: https://doi.org/10.1111/aas.14131.