Wear­able health tech­nol­o­gy brings research clos­er to peo­ple

Researchers at the Uni­ver­si­ty of Oulu are devel­op­ing inno­va­tions to mon­i­tor health. Exper­i­ments with real­is­tic mod­els, such as a can­cer-detect­ing bra, a leg sleeve for spot­ting blood clots, and a hel­met for track­ing radi­a­tion ther­a­py, offer a glimpse into future health­care.

Mariel­la Särestönie­mi togeth­er with Teemu Myl­lylä, Jar­mo Repo­nen, Mikael von und zu Fraun­berg, Juha Nikki­nen, Sami Myl­lymä­ki and her stu­dents, are devel­op­ing tech­nol­o­gy that could enable health mon­i­tor­ing and assess­ment with portable and wear­able mea­sur­ing devices. The research is part of the 6GESS research pro­gramme. Such devices could be used not only in hos­pi­tals but also in small­er health cen­ters. In a coun­try like Fin­land with long dis­tances, there is demand for this. Bring­ing research equip­ment clos­er to peo­ple low­ers the thresh­old for par­tic­i­pat­ing in stud­ies, which in turn means health issues can be detect­ed ear­li­er and addressed more effec­tive­ly.

“Instead of hav­ing to trav­el hun­dreds of kilo­me­ters to a hos­pi­tal for exam­i­na­tions, a per­son could go to their local health cen­ter for a quick pre­lim­i­nary scan. This new tech­nol­o­gy thus increas­es region­al equal­i­ty in health­care,” Särestönie­mi illus­trates the ben­e­fits of the emerg­ing tech­nol­o­gy.

Microwaves detect tumors safe­ly and quick­ly

Mariel­la Särestönie­mi specif­i­cal­ly stud­ies the use of microwave tech­nol­o­gy in wire­less health appli­ca­tions. Microwave tech­nol­o­gy is based on the dif­fer­ent elec­tri­cal prop­er­ties of tis­sues. For mea­sure­ment, researchers are devel­op­ing portable or light­weight wear­able devices, in which the radio sig­nal trav­el­ing between installed anten­nas can be ana­lyzed to detect anom­alies such as tumors. The low-pow­er microwave sig­nal is safe and effec­tive.

“For exam­ple, a sig­nal sent through brain or breast tis­sue behaves dif­fer­ent­ly when it encoun­ters dif­fer­ent tis­sues, which pro­vides data for the doc­tor inter­pret­ing it,” Särestönie­mi explains.

The tech­nol­o­gy is well-suit­ed for wear­able devices, as the nec­es­sary com­po­nents are small and inex­pen­sive.

“Devel­op­ing such devices for use in health cen­ters or even ambu­lances is there­fore real­is­tic,” Särestönie­mi says.

Anoth­er advan­tage of tech­nol­o­gy is speed.

“It takes only a few nanosec­onds for a microwave sig­nal to pass through, for exam­ple, the head. The mea­sure­ment process is quick and effort­less.”

Tumor-Detect­ing bras to help with mam­mog­ra­phy chal­lenges

Särestönie­mi envi­sions a new, effort­less way to par­tic­i­pate in breast can­cer screen­ing using microwave-based mea­sure­ment, in addi­tion to tra­di­tion­al mam­mog­ra­phy. Many women skip screen­ing because mam­mog­ra­phy is per­ceived as painful or the jour­ney to the exam­i­na­tion is too long.

“Mam­mog­ra­phy does not detect tumors in all breast types, which in any case requires addi­tion­al exam­i­na­tions. The devices under devel­op­ment could solve many of mammography’s chal­lenges.”

Microwave-based breast can­cer mon­i­tor­ing devices are already being clin­i­cal­ly test­ed across Europe. Särestöniemi’s goal is to devel­op mon­i­tor­ing bras along­side these larg­er devices, enabling pre­lim­i­nary checks in small­er health cen­ters, where they could even be used inde­pen­dent­ly. The device, worn briefly, would mea­sure and auto­mat­i­cal­ly send the data to the treat­ing physi­cian.

“The pro­ce­dure is intend­ed to be as easy and quick as mea­sur­ing blood pres­sure,” Särestönie­mi describes.

Anoth­er vision for a self-use device is a leg sleeve that detects blood clots. After surgery, the risk of blood clots is ele­vat­ed, so it would be use­ful if the patient could mon­i­tor signs of clot for­ma­tion at home. The sleeve could be pulled on a few times a day to check the sit­u­a­tion.

A new way to mon­i­tor radi­a­tion ther­a­py effects afford­ably and effec­tive­ly

The newest appli­ca­tion, which has sparked much inter­est among doc­tors, relates to mon­i­tor­ing the effects of radi­a­tion ther­a­py in treat­ing brain tumors. In cer­tain cas­es, the tumor is treat­ed pri­mar­i­ly with radi­a­tion ther­a­py instead of surgery.

The effects of radi­a­tion ther­a­py should be mon­i­tored fre­quent­ly to assess whether the treat­ment is suf­fi­cient or if oth­er meth­ods need to be con­sid­ered. Cur­rent imag­ing meth­ods are either expen­sive or use harm­ful radi­a­tion, which is why they can­not be per­formed very often,” Särestönie­mi explains.

Researchers are design­ing a light­weight hel­met for head mon­i­tor­ing, which the patient wears dur­ing scan­ning. Analy­sis of the microwave sig­nal trav­el­ing between anten­nas placed around the hel­met reveals whether the treat­ment has been effec­tive and the tumor has shrunk. Pre­lim­i­nary research results show that microwave tech­nol­o­gy can detect even small changes in tumor size.

“Radi­a­tion ther­a­py spe­cial­ists are very inter­est­ed in this, as it would allow for more fre­quent mon­i­tor­ing of treat­ment safe­ly.”

Real­is­tic mod­els account for dif­fer­ent human bod­ies

In Oulu, researchers aim to con­sid­er dif­fer­ent body types as thor­ough­ly as pos­si­ble and test the tech­nol­o­gy in chal­leng­ing sit­u­a­tions. This helps deter­mine whether the new tech­nolo­gies work in real-life sce­nar­ios with diverse indi­vid­u­als.

“For exam­ple, breast tis­sue types dif­fer sig­nif­i­cant­ly depend­ing on the amount of glan­du­lar and fat­ty tis­sue. The dif­fer­ences in prop­er­ties between glan­du­lar and tumor tis­sue are rel­a­tive­ly small com­pared to fat­ty tis­sue and tumors. Detect­ing a tumor is much more dif­fi­cult if the breast con­tains a lot of glan­du­lar tis­sue.”

The tis­sue mod­els used by researchers are made in an envi­ron­men­tal­ly friend­ly way from cook­ing ingre­di­ents.

“Once the mea­sure­ments are com­plet­ed, the mod­els can be dis­posed of as biowaste. We can eas­i­ly and quick­ly make new mod­els and adjust their size,” Särestönie­mi says.

Many tech­nolo­gies are being researched, but the appli­ca­tions are not yet in use. If all goes well and clin­i­cal tri­als prove suc­cess­ful, microwave-based appli­ca­tions could be in use in health cen­ters with­in ten years.

“Microwave tech­nol­o­gy is con­sid­ered very promis­ing and is already under­go­ing clin­i­cal test­ing in Euro­pean hos­pi­tals,” Särestönie­mi states.

Source (text and image): The Uni­ver­si­ty of Oulu

In the pic­ture senior researcher Mariel­la Särestönie­mi in the Human Body Twin Lab­o­ra­to­ry.